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Treatment of Inferior Epigastric Pseudoaneurysm and Rectus Sheath Hematoma through Percutaneous Direct Sac Puncture and Embolization with N-Butyl Cyanoacrylate

Hematomas within the rectus sheath, often seen in the elderly who are on blood-thinning medication, can necessitate embolization when faced with significant blood pressure instability or vascular damage...

Treatment of Inferior Epigastric Pseudoaneurysm and Rectus Sheath Hematoma through Percutaneous...
Treatment of Inferior Epigastric Pseudoaneurysm and Rectus Sheath Hematoma through Percutaneous Direct Sac Puncture and Embolization with NBCA

Treatment of Inferior Epigastric Pseudoaneurysm and Rectus Sheath Hematoma through Percutaneous Direct Sac Puncture and Embolization with N-Butyl Cyanoacrylate

In a recent medical case, a 72-year-old female with a history of heart failure with preserved ejection fraction (HFpEF), atrial fibrillation on Eliquis, and an abdominal aortic aneurysm (AAA) status post endovascular aneurysm repair (EVAR), complicated by Type 2 endoleak, presented with worsening abdominal pain and swelling.

Upon examination, the Computed Tomography Angiography (CTA) of the abdomen and pelvis revealed a large left rectus sheath hematoma with a left inferior epigastric pseudoaneurysm, but no evidence of active extravasation (Figs. 1 and 2). The patient was subsequently discharged from an outside hospital after conservative treatment, but re-bleeding occurred, necessitating further intervention.

The patient presented to the ED with worsening abdominal swelling and pain. On presentation, the patient was hemodynamically stable with a hemoglobin level of 8.5, which subsequently downtrended to 6.3. Given the complex vascular anatomy and body habitus, an intra-arterial approach was limited.

Interventional Radiology (IR) was consulted for embolization (Fig. 3). The left inferior epigastric pseudoaneurysm was treated by percutaneous direct sac puncture with N-butyl cyanoacrylate (NBCA) glue. This method offers several advantages, including high effectiveness, rapid hemostasis, and a minimally invasive nature.

NBCA, a liquid embolic agent, polymerizes quickly on contact with blood, allowing prompt embolization even in complex, difficult-to-access vascular territories where conventional methods might fail or be risky. Its strong and rapid occlusion provides fast and permanent sealing of bleeding vessels, which is crucial in pseudoaneurysms and hematomas where bleeding control must be definitive.

Moreover, NBCA can be precisely delivered via microcatheters into small or tortuous vessels such as the inferior epigastric artery, which is often anatomically challenging. Its minimally invasive treatment avoids open surgery, thus reducing patient morbidity, shortening hospital stays, and lowering complication risks compared to surgical options.

The rectus sheath has additional vascular supply from the superficial epigastric artery and, rarely, the deep circumflex iliac artery. Superficial pseudoaneurysms with challenging vascular anatomy may benefit from direct percutaneous approaches, often treated with thrombin. However, NBCA embolization offers an alternative to conventional thrombin injection or Transcatheter Arterial Embolization (TAE).

Re-bleeding remains a problem with TAE due to retrograde flow from collaterals, vessel recanalization, and loss of tamponade effect. NBCA's effectiveness in complex anatomy and applicability in refractory cases makes it an ideal embolic agent for controlling bleeding in vascular territories with challenging anatomy, such as inferior epigastric pseudoaneurysms and rectus sheath hematomas.

While no direct, dedicated study on NBCA specifically for inferior epigastric pseudoaneurysm or rectus sheath hematoma was found, the evidence for NBCA's effectiveness in complex vascular embolization and gastrointestinal bleeding refractory to conventional treatment strongly supports these advantages.

This case highlights the use of NBCA for direct sac puncture and embolization of an inferior epigastric pseudoaneurysm, providing an alternative to conventional methods in challenging vascular anatomy cases.

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